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Conservation analysis and pathogenicity prediction of mutant genes of ectodysplasin a

BACKGROUND: Hypohidrotic ectodermal dysplasia (HED) is a common recessive X-linked hereditary disease that affects the development of ectoderm. Gene mutations of ectodysplasin A (EDA) play key roles in process of this disease. In our preliminary study, three unknown mutation sites (c.878 T > G, c...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: He, Fangqi, Wang, Hongfeng, Zhang, Xiaoyu, Gao, Qingping, Guo, Feng, Chen, Chang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286515/
https://ncbi.nlm.nih.gov/pubmed/30526585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-018-0726-2
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