Using a three-compartment model improves the estimation of iohexol clearance to assess glomerular filtration rate

Plasma clearance of iohexol is a key tool to precisely determine glomerular filtration rate (GFR) in clinical research and clinical practice. Despite evidence that iohexol pharmacokinetics are described best by three-compartment models, two-compartment approaches (Schwartz approach) are customary, w...

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Udgivet i:Sci Rep
Main Authors: Taubert, Max, Ebert, Natalie, Martus, Peter, van der Giet, Markus, Fuhr, Uwe, Schaeffner, Elke
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286374/
https://ncbi.nlm.nih.gov/pubmed/30531802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35989-x
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