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In Vivo Evaluation of PAX6 Overexpression and NMDA Cytotoxicity to Stimulate Proliferation in the Mouse Retina

Retinal degenerative diseases, due to the lack of regeneration systems and self-renewable cells, often lead to visual impairment. Pax6 is a pleiotropic transcription factor and its expression level determines self-renewal status or differentiation of retinal cells. Here, we investigated the fate of...

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Publicado en:Sci Rep
Main Authors: Ranaei Pirmardan, Ehsan, Soheili, Zahra-Soheila, Samiei, Shahram, Ahmadieh, Hamid, Mowla, Seyed Javad, Naseri, Marzieh, Daftarian, Narsis
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286369/
https://ncbi.nlm.nih.gov/pubmed/30531887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35884-5
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