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Safety evaluation of frequent application of microbubble-enhanced focused ultrasound blood-brain-barrier opening

Focused ultrasound (FUS) with the presence of microbubbles induces blood brain barrier (BBB) opening in targeted areas and facilitates drug delivery. However, recent studies have indicated that FUS-BBB opening with excessive exposure levels may be associated with inflammatory response and cellular/t...

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Foilsithe in:Sci Rep
Main Authors: Tsai, Hong-Chieh, Tsai, Chih-Hung, Chen, Wen-Shiang, Inserra, Claude, Wei, Kuo-Chen, Liu, Hao-Li
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286368/
https://ncbi.nlm.nih.gov/pubmed/30531863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35677-w
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