Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques

An effective HIV vaccine will likely need to induce broad and potent CTL responses. Epitope-based vaccines offer significant potential for inducing multi-specific CTL, but often require conjugation to T helper epitopes or carrier moieties to induce significant responses. We tested hybrid DNA vaccine...

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Enregistré dans:
Détails bibliographiques
Publié dans:Virology
Auteurs principaux: Fuller, Deborah Heydenburg, Shipley, Tim, Allen, Todd M., Fuller, James T., Wu, Mary S., Horton, Helen, Wilson, Nancy, Widera, Georg, Watkins, David I.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286304/
https://ncbi.nlm.nih.gov/pubmed/17428516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.02.024
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