The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

The biogenesis of 60S ribosomal subunits is initiated in the nucleus where rRNAs and proteins form pre-60S particles. These pre-60S particles mature by transiently interacting with various assembly factors. The ~5000 amino-acid AAA+ ATPase Rea1 (or Midasin) generates force to mechanically remove ass...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Sosnowski, Piotr, Urnavicius, Linas, Boland, Andreas, Fagiewicz, Robert, Busselez, Johan, Papai, Gabor, Schmidt, Helgo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2018
Pynciau:
Structural Biology and Molecular Biophysics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286127/
https://ncbi.nlm.nih.gov/pubmed/30460895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39163
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