A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

Intracellular lipopolysaccharide (LPS) triggers the non-canonical inflammasome pathway, resulting in pyroptosis of innate immune cells. In addition to its well-known proinflammatory role, LPS can directly cause regression of some tumors, although the underlying mechanism has remained unknown. Here w...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yokoyama, Shigetoshi, Cai, Yan, Murata, Miyuki, Tomita, Takeshi, Yoneda, Mitsuhiro, Xu, Lei, Pilon, Aprile L, Cachau, Raul E, Kimura, Shioko
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286126/
https://ncbi.nlm.nih.gov/pubmed/30526845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37854
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