Treatment with XAV-939 prevents in vitro calcification of human valvular interstitial cells

The development of a substance or inhibitor-based treatment strategy for the prevention of aortic valve stenosis is a challenge and a main focus of medical research in this area. One strategy may be to use the tankyrase inhibitor XAV-939, which leads to Axin stabilisation and subsequent destruction...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Dittfeld, Claudia, Reimann, Gabriel, Mieting, Alice, Büttner, Petra, Jannasch, Anett, Plötze, Katrin, Steiner, Gerald, Tugtekin, Sems Malte, Matschke, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286025/
https://ncbi.nlm.nih.gov/pubmed/30532256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208774
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