Cardioprotective Effects of Paricalcitol Alone and in Combination With FGF23 Receptor Inhibition in Chronic Renal Failure: Experimental and Clinical Studies

BACKGROUND: In uremic animals, vitamin D receptor (VDR) agonists like paricalcitol (Pc) attenuate cardiac hypertrophy, but this effect has not been replicated consistently in humans with chronic kidney disease. Elevated fibroblast growth factor 23 (FGF23) levels cause cardiac hypertrophy with activa...

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Detalhes bibliográficos
Publicado no:Am J Hypertens
Main Authors: Czaya, Brian, Seeherunvong, Wacharee, Singh, Saurav, Yanucil, Christopher, Ruiz, Phillip, Quiroz, Yasmir, Grabner, Alexander, Katsoufis, Chryso, Swaminathan, Sethuraman, Abitbol, Carolyn, Rodriguez-Iturbe, Bernardo, Faul, Christian, Freundlich, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284753/
https://ncbi.nlm.nih.gov/pubmed/30329020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpy154
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