Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway

PURPOSE: Liver fibrosis is a worldwide health issue. Development of effective new drugs for treatment of this disease is of great importance. This study investigated the therapeutic effects of ferulic acid on liver fibrosis in vitro and in vivo. MATERIALS AND METHODS: Human hepatic stellate cell lin...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Mu, Mao, Zuo, Shi, Wu, Rong-Min, Deng, Kai-Sheng, Lu, Shuang, Zhu, Juan-Juan, Zou, Gao-Liang, Yang, Jing, Cheng, Ming-Liang, Zhao, Xue-Ke
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284527/
https://ncbi.nlm.nih.gov/pubmed/30584275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S186726
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