Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression

BACKGROUND: Glioblastoma (GBM) is the most frequent and malignant primary brain tumor in adults and despite the progress in surgical procedures and therapy options, the overall survival remains very poor. Glutamate and α-KG are fundamental elements necessary to support the growth and proliferation o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EBioMedicine
Prif Awduron: Franceschi, Sara, Corsinovi, Debora, Lessi, Francesca, Tantillo, Elena, Aretini, Paolo, Menicagli, Michele, Scopelliti, Claudia, Civita, Prospero, Pasqualetti, Francesco, Naccarato, Antonio G., Ori, Michela, Mazzanti, Chiara M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2018
Pynciau:
Research paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284416/
https://ncbi.nlm.nih.gov/pubmed/30314897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.008
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