Sex-Related Differences in Lactotroph Tumor Aggressiveness Are Associated With a Specific Gene-Expression Signature and Genome Instability

Sex-related differences have been reported in various cancers, in particular men with lactotroph tumors have a worse prognosis than women. While the underlying mechanism of this sexual dimorphism remains unclear, it has been suggested that a lower estrogen receptor alpha expression may drive the sex...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Wierinckx, Anne, Delgrange, Etienne, Bertolino, Philippe, François, Patrick, Chanson, Philippe, Jouanneau, Emmanuel, Lachuer, Joël, Trouillas, Jacqueline, Raverot, Gérald
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283894/
https://ncbi.nlm.nih.gov/pubmed/30555413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00706
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