Single-molecule imaging correlates decreasing nuclear volume with increasing TF-chromatin associations during zebrafish development

Zygotic genome activation (ZGA), the onset of transcription after initial quiescence, is a major developmental step in many species, which occurs after ten cell divisions in zebrafish embryos. How transcription factor (TF)-chromatin interactions evolve during early development to support ZGA is larg...

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Pubblicato in:Nat Commun
Autori principali: Reisser, Matthias, Palmer, Anja, Popp, Achim P., Jahn, Christopher, Weidinger, Gilbert, Gebhardt, J. Christof M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283880/
https://ncbi.nlm.nih.gov/pubmed/30523256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07731-8
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