Molecular Interface of Neuronal Innate Immunity, Synaptic Vesicle Stabilization and Presynaptic Homeostatic Plasticity

We define a homeostatic function for innate immune signaling within neurons. A genetic analysis of the innate immune signaling genes IMD, IKKβ, Tak1 and Relish demonstrates that each is essential for presynaptic homeostatic plasticity (PHP). Subsequent analyses define how the rapid induction of PHP...

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Publicado en:Neuron
Autores principales: Harris, Nathan, Fetter, Richard D., Brasier, DJ, Tong, Amy, Davis, Graeme W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283688/
https://ncbi.nlm.nih.gov/pubmed/30344041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.09.048
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