Molecular Interface of Neuronal Innate Immunity, Synaptic Vesicle Stabilization and Presynaptic Homeostatic Plasticity

We define a homeostatic function for innate immune signaling within neurons. A genetic analysis of the innate immune signaling genes IMD, IKKβ, Tak1 and Relish demonstrates that each is essential for presynaptic homeostatic plasticity (PHP). Subsequent analyses define how the rapid induction of PHP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuron
Prif Awduron: Harris, Nathan, Fetter, Richard D., Brasier, DJ, Tong, Amy, Davis, Graeme W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283688/
https://ncbi.nlm.nih.gov/pubmed/30344041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.09.048
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