E4orf1: A protein for enhancing glucose uptake despite impaired proximal insulin signaling

BACKGROUND: Type 2 diabetes is often linked with impaired proximal insulin signaling. Hence, a therapeutic agent that enhances cellular glucose uptake without requiring proximal insulin signaling would be desirable for improving glycemic control. The E4orf1 peptide (E4) derived from human adenovirus...

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Udgivet i:PLoS One
Main Authors: Shastri, Anuradha A., Hegde, Vijay, Peddibhotla, Swetha, Feizy, Zahra, Dhurandhar, Nikhil V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283569/
https://ncbi.nlm.nih.gov/pubmed/30521580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208427
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