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Progesterone-Mediated Inhibition of the GnRH Pulse Generator: Differential Sensitivity as a Function of Sleep Status

CONTEXT: During normal, early puberty, luteinizing hormone (LH) pulse frequency is low while awake but increases during sleep. Mechanisms underlying such changes are unclear, but a small study in early pubertal girls suggested that differential wake-sleep sensitivity to progesterone negative feedbac...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Kim, Su Hee, Lundgren, Jessica A, Bhabhra, Ruchi, Collins, Jessicah S, Patrie, James T, Burt Solorzano, Christine M, Marshall, John C, McCartney, Christopher R
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283412/
https://ncbi.nlm.nih.gov/pubmed/29300925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-02299
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