Evaluation of Potential Disease‐Mediated Drug–Drug Interaction in Patients With Moderate‐to‐Severe Atopic Dermatitis Receiving Dupilumab

This open‐label drug–drug interaction study assessed whether blockade by dupilumab of interleukin (IL)‐4 and IL‐13 signaling affects the pharmacokinetics of drugs metabolized by cytochrome P450 (CYP450) enzymes. The pharmacokinetics of five CYP450 substrates given orally (midazolam, omeprazole, S‐wa...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Clin Pharmacol Ther
Auteurs principaux: Davis, John D., Bansal, Ashish, Hassman, David, Akinlade, Bolanle, Li, Meng, Li, Zhaoyang, Swanson, Brian, Hamilton, Jennifer D., DiCioccio, A. Thomas
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282936/
https://ncbi.nlm.nih.gov/pubmed/29498038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1058
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires