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Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is an increasingly prevalent nonalcoholic fatty liver disease, characterized by inflammatory cell infiltration and hepatocellular damage. Mammalian target of rapamycin complex 1 (mTORC1) has been investigated extensively in the context of ca...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Liu, Wenli, Ye, Chenji, Cheng, Qian, Zhang, Xuejiao, Yao, Liu, Li, Qi, Huang, Jing, Liu, Yajin, Zou, Zhengsheng, Wang, Hua, Yan, Jun, Zhu, Yi, Wang, Chunjiong, Ai, Ding
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282883/
https://ncbi.nlm.nih.gov/pubmed/30539788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.09.011
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