Fluctuations in p53 signaling allow escape from cell cycle arrest

Biological signals need to be robust and filter small fluctuations, yet maintain sensitivity to signals across a wide range of magnitudes. Here we studied how fluctuations in DNA damage signaling relate to maintenance of long-term cell cycle arrest. Using live-cell imaging, we quantified division pr...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Reyes, José, Chen, Jia-Yun, Stewart-Ornstein, Jacob, Karhohs, Kyle W., Mock, Caroline S., Lahav, Galit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282757/
https://ncbi.nlm.nih.gov/pubmed/30057196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.031
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