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The BRAF(V600E) mutation in papillary thyroid microcarcinoma with intermediate-risk to high-risk features: does the mutation have an effect on clinical response to radioiodine therapy?

OBJECTIVES: Preclinical studies showed that BRAF(V600E) mutation significantly reduced radioiodine uptake and decreased the sensitivity to radioactive iodine (RAI) therapy. However, clinical data regarding its role in therapeutic decision making with respect to RAI therapy are currently insufficient...

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Bibliografische gegevens
Gepubliceerd in:Nucl Med Commun
Hoofdauteurs: Shen, Guohua, Kou, Ying, Liu, Bin, Huang, Rui, Kuang, Anren
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282664/
https://ncbi.nlm.nih.gov/pubmed/30312216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNM.0000000000000930
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