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Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study

BACKGROUND: Aryl hydrocarbon receptor (AhR) ligands may act as potential carcinogens or anti-tumor agents. Understanding how some of the residues in AhR ligand binding domain (AhRLBD) modulate their interactions with ligands would be useful in assessing their divergent roles including toxic and bene...

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Publicat a:BMC Struct Biol
Autors principals: Chitrala, Kumaraswamy Naidu, Yang, Xiaoming, Nagarkatti, Prakash, Nagarkatti, Mitzi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282305/
https://ncbi.nlm.nih.gov/pubmed/30522477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-018-0095-2
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