Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 (MSP-1) among Plasmodium knowlesi samples from Malaysia

BACKGROUND: The merozoite surface protein-1 (MSP-1) gene encodes for a leading malaria vaccine candidate antigen. However, its extensive polymorphic nature represents a major obstacle to the development of a protective vaccine. Previously, a pilot study was carried out to explore the sequence variat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Parasit Vectors
Prif Awduron: Yap, Nan Jiun, Vythilingam, Indra, Hoh, Boon Peng, Goh, Xiang Ting, Muslim, Azdayanti, Ngui, Romano, Rajoo, Yamuna, Choy, Seow Huey, William, Timothy, Yeo, Tsin Wen, Lim, Yvonne Ai-Lian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282282/
https://ncbi.nlm.nih.gov/pubmed/30518419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-018-3234-5
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