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Cryptococcus neoformans, Unlike Candida albicans, Forms Aneuploid Clones Directly from Uninucleated Cells under Fluconazole Stress

Heteroresistance to fluconazole (FLC) in Cryptococcus is a transient adaptive resistance which is lost upon release from the drug pressure. It is known that clones heteroresistant to FLC invariably contain disomic chromosomes, but how disomy is formed remains unclear. Previous reports suggested that...

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發表在:mBio
Main Authors: Chang, Yun C., Khanal Lamichhane, Ami, Kwon-Chung, Kyung J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282203/
https://ncbi.nlm.nih.gov/pubmed/30514783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01290-18
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