Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention

Non-steroidal anti-inflammatory drugs (NSAIDs) can damage the small intestine, mainly through an involvement of enteric bacteria. This study examined the pathophysiology of NSAID-associated intestinal lesions in a rat model of diclofenac-enteropathy and evaluated the effect of rifaximin on small bow...

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Publicado en:Front Pharmacol
Autores principales: Colucci, Rocchina, Pellegrini, Carolina, Fornai, Matteo, Tirotta, Erika, Antonioli, Luca, Renzulli, Cecilia, Ghelardi, Emilia, Piccoli, Elena, Gentile, Daniela, Benvenuti, Laura, Natale, Gianfranco, Fulceri, Federica, Palazón-Riquelme, Pablo, López-Castejón, Gloria, Blandizzi, Corrado, Scarpignato, Carmelo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281992/
https://ncbi.nlm.nih.gov/pubmed/30555323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01340
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