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Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model

Recent studies on tissue-autonomous serotonin (5-hydroxytryptamine [5-HT]) function have identified new roles for 5-HT in peripheral organs. Most of these studies were performed by crossing mice carrying the Tph1(tm1Kry) allele with tissue specific Cre mice. In the present study, we found that 5-HT...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Hyeongseok, Kim, Yeong Gi, Choi, Wonsuk, Moon, Joon Ho, Hwang, Inseon, Kim, Kyuho, Yadav, Vijay K., Karsenty, Gerard, Jeong, Ji-Seon, Kim, Hail
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281741/
https://ncbi.nlm.nih.gov/pubmed/30518775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36097-6
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