Sodium selenite inhibits deoxynivalenol-induced injury in GPX1-knockdown porcine splenic lymphocytes in culture

Deoxynivalenol (DON) is a cytotoxic mycotoxin that can cause cell damages. The main effect is to inhibit protein synthesis. Oxidative stress is one of the effects of DON. Selenium (Se) can ameliorate the cell damage caused by DON-induced oxidative stress, but it is unclear whether through selenoprot...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ren, Zhihua, Fan, Yu, Zhang, Zhuo, Chen, Chaoxi, Chen, Changhao, Wang, Xuemei, Deng, Junliang, Peng, Guangneng, Hu, Yanchun, Cao, Suizhong, Yu, Shumin, Ma, Xiaoping, Shen, Liuhong, Zhong, Zhijun, Zhou, Ziyao, Xu, Zhiwen, Zuo, Zhicai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281670/
https://ncbi.nlm.nih.gov/pubmed/30518949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36149-x
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