The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells

Semaphorin 6A (SEMA6A), a membrane-bound protein, is downregulated in lung cancer tissue compared to its adjacent normal tissue. However, the functions of SEMA6A in lung cancer cells are still unclear. In the present study, full length SEMA6A and various truncations were transfected into lung cancer...

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Publicado no:Oncogenesis
Main Authors: Shen, Cheng-Ying, Chang, Ya-Chu, Chen, Li-Han, Lin, Wen-Chun, Lee, Yung-Hua, Yeh, Shu-Tsen, Chen, Hsin-Kuang, Fang, Wentao, Hsu, Chung-Ping, Lee, Jang-Ming, Lu, Tzu-Pin, Hsiao, Pei-Wen, Lai, Liang-Chuan, Tsai, Mong-Hsun, Chuang, Eric Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281666/
https://ncbi.nlm.nih.gov/pubmed/30518871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0105-z
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