Lecithin-Stabilized Polymeric Micelles (L(sb)PMs) for Delivering Quercetin: Pharmacokinetic Studies and Therapeutic Effects of Quercetin Alone and in Combination with Doxorubicin

In this study, lecithin-stabilized polymeric micelles (L(sb)PMs) were prepared to load quercetin (QUE) in order to improve its bioavailability and increase its antitumor activity. Its combination with doxorubicin (DOX) to minimize DOX-mediated cardiac toxicity and increase the antitumor activity of...

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Vydáno v:Sci Rep
Hlavní autoři: Chang, Chia-En, Hsieh, Chien-Ming, Huang, Sheng-Chin, Su, Chia-Yu, Sheu, Ming-Thau, Ho, Hsiu-O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281656/
https://ncbi.nlm.nih.gov/pubmed/30518853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36162-0
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