Differential effects of type 1 diabetes mellitus and subsequent osteoblastic β-catenin activation on trabecular and cortical bone in a mouse model

Type 1 diabetes mellitus (T1DM) is a pathological condition associated with osteopenia. WNT/β-catenin signaling is implicated in this process. Trabecular and cortical bone respond differently to WNT/β-catenin signaling in healthy mice. We investigated whether this signaling has different effects on...

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Vydáno v:Exp Mol Med
Hlavní autoři: Chen, Sixu, Liu, Daocheng, He, Sihao, Yang, Lei, Bao, Quanwei, Qin, Hao, Liu, Huayu, Zhao, Yufeng, Zong, Zhaowen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281645/
https://ncbi.nlm.nih.gov/pubmed/30518745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0186-y
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