p73 regulates ependymal planar cell polarity by modulating actin and microtubule cytoskeleton

Planar cell polarity (PCP) and intercellular junctional complexes establish tissue structure and coordinated behaviors across epithelial sheets. In multiciliated ependymal cells, rotational and translational PCP coordinate cilia beating and direct cerebrospinal fluid circulation. Thus, PCP disruptio...

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Pubblicato in:Cell Death Dis
Autori principali: Fuertes-Alvarez, Sandra, Maeso-Alonso, Laura, Villoch-Fernandez, Javier, Wildung, Merit, Martin-Lopez, Marta, Marshall, Clayton, Villena-Cortes, Alberto J., Diez-Prieto, Inmaculada, Pietenpol, Jennifer A., Tissir, Fadel, Lizé, Muriel, Marques, Margarita M., Marin, Maria C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281643/
https://ncbi.nlm.nih.gov/pubmed/30518789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1205-6
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