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HCRP-1 regulates EGFR–AKT–BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer

Hepatocellular carcinoma-related protein-1 (HCRP-1), a subunit of mammalian endosomal sorting complex required for transport-I (ESCRT-I), is frequently downregulated in various kinds of malignant tumors. The role of HCRP-1 in colorectal cancer (CRC) remains unknown. We investigate the clinical value...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chen, Feifei, Zhang, Lei, Wu, Jianqiang, Huo, Fuchun, Ren, Xin, Zheng, Junnian, Pei, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281589/
https://ncbi.nlm.nih.gov/pubmed/30518879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1217-2
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