Effects of insulin-loaded chitosan-alginate nanoparticles on RAGE expression and oxidative stress status in the kidney tissue of rats with type 1 diabetes

OBJECTIVE(S): Chronic hyperglycemia leads to activation of the advanced glycation end products (AGE)-receptor (RAGE) for AGE axis and oxidative stress, which promote diabetic renal damage. This study examines the effect of insulin-loaded trimethyl chitosan nanoparticles on the kidney tissue of diabe...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Heidarisasan, Shirin, Ziamajidi, Nasrin, Karimi, Jamshid, Abbasalipourkabir, Roghayeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281063/
https://ncbi.nlm.nih.gov/pubmed/30524677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2018.28463.6899
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