A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia

Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) represents the most common genetic subtype of adult ALL (20%–30%) and accounts for approximately 50% of all cases in the elderly. It has been considered the subgroup of ALL with the worst outcome. The introduction of tyrosine ki...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Vinhas, Raquel, Lourenço, Alexandra, Santos, Susana, Lemos, Marcos, Ribeiro, Patrícia, de Sousa, Aida Botelho, Baptista, Pedro Viana, Fernandes, Alexandra Ramos
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280987/
https://ncbi.nlm.nih.gov/pubmed/30584318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S177019
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