Sprouty2 enhances the tumorigenic potential of glioblastoma cells

BACKGROUND: Sprouty2 (SPRY2), a feedback regulator of receptor tyrosine kinase (RTK) signaling, has been shown to be associated with drug resistance and cell proliferation in glioblastoma (GBM), but the underlying mechanisms are still poorly defined. METHODS: SPRY2 expression and survival patterns o...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Park, Jong-Whi, Wollmann, Guido, Urbiola, Carles, Fogli, Barbara, Florio, Tullio, Geley, Stephan, Klimaschewski, Lars
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280149/
https://ncbi.nlm.nih.gov/pubmed/29635363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy028
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