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Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

BACKGROUND: Primary glioblastoma cell (GC) cultures have emerged as a key model in brain tumor research, with the potential to uncover patient-specific differences in therapy response. However, there is limited quantitative information about the stability of such cells during the initial 20–30 passa...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Baskaran, Sathishkumar, Mayrhofer, Markus, Kultima, Hanna Göransson, Bergström, Tobias, Elfineh, Lioudmila, Cavelier, Lucia, Isaksson, Anders, Nelander, Sven
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280139/
https://ncbi.nlm.nih.gov/pubmed/29462414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy024
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