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Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS

A reliable and fast liquid chromatography-tandem mass spectrometry method has been developed for the simultaneous determination of three oxidized nucleic acid damage products in urine, 8-oxoguanine (8-oxoGua), 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo)....

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Shih, Ying-Ming, Cooke, Marcus S., Pan, Chih-Hong, Chao, Mu-Rong, Hu, Chiung-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279954/
https://ncbi.nlm.nih.gov/pubmed/30508700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.11.016
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