Methylation of High-Risk Human Papillomavirus Genomes are Associated with Cervical Precancer in HIV-positive Women

BACKGROUND: HIV-positive women are at substantial risk of HPV-associated cervical neoplasia caused by high-risk (HR) HPVs. Methylation of the HPV genome is associated with cervical intraepithelial neoplasia grade 3 (CIN3) in HIV-negative women, yet it is unknown whether this holds true for HIV-posit...

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Publicado en:Cancer Epidemiol Biomarkers Prev
Autores principales: Gradissimo, Ana, Lam, Jessica, Attonito, John D., Palefsky, Joel, Massad, L. Stewart, Xie, Xianhong, Eltoum, Isam-Eldin, Rahangdale, Lisa, Fischl, Margaret A., Anastos, Kathryn, Minkoff, Howard, Xue, Xiaonan, D’Souza, Gypsyamber, Flowers, Lisa C., Colie, Christine, Shrestha, Sadeep, Hessol, Nancy A., Strickler, Howard D., Burk, Robert D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279505/
https://ncbi.nlm.nih.gov/pubmed/30237251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-17-1051
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