Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1

The mammalian cochlea contains two types of mechanosensory hair cells (HCs) that play different and critical roles in hearing. Inner hair cells (IHCs), with an elaborate presynaptic apparatus, signal to cochlear neurons and communicate sound information to the brain. Outer hair cells (OHCs) mechanic...

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Publicado no:Nature
Main Authors: Wiwatpanit, Teerawat, Lorenzen, Sarah M., Cantú, Jorge A., Foo, Chuan Zhi, Hogan, Ann K., Márquez, Freddie, Clancy, John C., Schipma, Matthew J., Cheatham, Mary Ann, Duggan, Anne, García-Añoveros, Jaime
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279423/
https://ncbi.nlm.nih.gov/pubmed/30305733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0570-8
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