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Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes
SipA is a major effector of Salmonella, which causes gastroenteritis and enteric fever. Caspase-3 cleaves SipA into two domains: the C-terminal domain regulates actin polymerization, whereas the function of the N terminus is unknown. We show that the cleaved SipA N terminus binds and recruits host S...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279372/ https://ncbi.nlm.nih.gov/pubmed/30309979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802155 |
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