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Sphingosine kinase 1 overexpression contributes to sunitinib resistance in clear cell renal cell carcinoma
Sphingosine kinase 1 (SphK1) is the major source of the bioactive lipid and GPCR agonist sphingosine 1-phosphate (S1P). Although alterations in SphK1 expression and activity have been detected in various human malignancies, its potential molecular mechanisms in the development and sunitinib resistan...
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| Publié dans: | Oncoimmunology |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279321/ https://ncbi.nlm.nih.gov/pubmed/30524898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1502130 |
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