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Ca(2+)-Sensor Neurocalcin δ and Hormone ANF Modulate ANF-RGC Activity by Diverse Pathways: Role of the Signaling Helix Domain

Prototype member of the membrane guanylate cyclase family, ANF-RGC (Atrial Natriuretic Factor Receptor Guanylate Cyclase), is the physiological signal transducer of two most hypotensive hormones ANF and BNP, and of the intracellular free Ca(2+). Both the hormonal and the Ca(2+)-modulated signals ope...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Duda, Teresa, Pertzev, Alexandre, Ravichandran, Sarangan, Sharma, Rameshwar K.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278801/
https://ncbi.nlm.nih.gov/pubmed/30546296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00430
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