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Synthesis and Biological Evaluation of Phaeosphaeride A Derivatives as Antitumor Agents

New derivatives of phaeosphaeride A (PPA) were synthesized and characterized. Anti-tumor activity studies were carried out on the HCT-116, PC3, MCF-7, A549, К562, NCI-Н929, Jurkat, THP-1, RPMI8228 tumor cell lines, and on the HEF cell line. All of the compounds synthesized were found to have better...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Abzianidze, Victoria, Beltyukov, Petr, Zakharenkova, Sofya, Moiseeva, Natalia, Mejia, Jennifer, Holder, Alvin, Trishin, Yuri, Berestetskiy, Alexander, Kuznetsov, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278656/
https://ncbi.nlm.nih.gov/pubmed/30469343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23113043
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