Lysyl Hydroxylase Inhibition by Minoxidil Blocks Collagen Deposition and Prevents Pulmonary Fibrosis via TGF-β(1)/Smad3 Signaling Pathway

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a deadly disease characterized by excessive collagen in the extracellular matrix (ECM) of the lungs. Collagen is the primary protein component of the ECM. However, the exact mechanisms underlying the formation and deposition of collagen in the ECM u...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Med Sci Monit
Hlavní autoři: Shao, Songjun, Zhang, Xiangning, Duan, Lingdi, Fang, Haiyan, Rao, Shanshan, Liu, Weijia, Guo, Bing, Zhang, Xiangyan
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2018
Témata:
Clinical Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278642/
https://ncbi.nlm.nih.gov/pubmed/30481795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910761
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky