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Identification of a 2′-O-Methyluridine Nucleoside Hydrolase Using the Metagenomic Libraries
Ribose methylation is among the most ubiquitous modifications found in RNA. 2′-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. Moreover, 2′-O-methylribonucleosides are promising starting materials for the production of nucleic acid-based drugs. Despite t...
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| Publicado en: | Molecules |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6278475/ https://ncbi.nlm.nih.gov/pubmed/30405065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112904 |
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