The Two Isoforms of Lyn Display Different Intramolecular Fuzzy Complexes with the SH3 Domain

The function of the intrinsically disordered Unique domain of the Src family of tyrosine kinases (SFK), where the largest differences between family members are concentrated, remains poorly understood. Recent studies in c-Src have demonstrated that the Unique region forms transient interactions, des...

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Bibliographic Details
Published in:Molecules
Main Authors: Teixeira, João M. C., Fuentes, Héctor, Bielskutė, Stasė, Gairi, Margarida, Żerko, Szymon, Koźmiński, Wiktor, Pons, Miquel
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278449/
https://ncbi.nlm.nih.gov/pubmed/30360468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112731
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