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In vitro effects of levosimendan on muscle of malignant hyperthermia susceptible and non-susceptible swine

BACKGROUND: The calcium sensitizer levosimendan is increasingly used to improve hemodynamics in patients with acutely decompensated heart failure. By binding to cardiac troponin C the conformation of the calcium-troponin C complex is stabilized, which leads to acceleration of actin-myosin crossbrigd...

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Bibliographic Details
Published in:BMC Anesthesiol
Main Authors: Schuster, Frank, Johannsen, Stephan, Isbary, Susanne, Türkmeneli, Ismail, Roewer, Norbert
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278068/
https://ncbi.nlm.nih.gov/pubmed/30509180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-018-0644-z
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