Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation

BACKGROUND: Colorectal cancer (CRC) is one of the most common digestive malignant tumors, and DMTN is a transcriptionally differentially expressed gene that was identified using CRC mRNA sequencing data from The Cancer Genome Atlas (TCGA). Our preliminary work suggested that the expression of DMTN w...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Ye, Ya-Ping, Jiao, Hong-Li, Wang, Shu-Yang, Xiao, Zhi-Yuan, Zhang, Dan, Qiu, Jun-Feng, Zhang, Ling-Jie, Zhao, Ya-Li, Li, Ting-Ting, Li-Liang, Liao, Wen-Ting, Ding, Yan-Qing
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277997/
https://ncbi.nlm.nih.gov/pubmed/30514346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0958-1
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