Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice

Chronic neuropathic pain is associated with anxiety- and depressive-like disorders. Its treatment remains a serious clinical problem due to the lack of efficacy of the available therapeutic modalities. We investigated if the activation of the transcription factor Nrf2 could modulate the nociceptive...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Ferreira-Chamorro, Pablo, Redondo, Alejandro, Riego, Gabriela, Leánez, Sergi, Pol, Olga
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277937/
https://ncbi.nlm.nih.gov/pubmed/30542282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01332
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