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MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
The histone variant macroH2A1 localizes to two functionally distinct chromatin subtypes marked by either H3K27me3 or H2B acetylations, where it is thought to directly regulate transcription. The recent finding, that macroH2A1 regulates mitochondrial respiration by globally dampening PARP activity, r...
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| Publicado no: | Nat Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277393/ https://ncbi.nlm.nih.gov/pubmed/30510186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07189-8 |
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