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Natriuretic Peptide Based Therapeutics For Heart Failure: Cenderitide: A Novel First-In-Class Designer Natriuretic Peptide

Cenderitide is a novel designer natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide was engineered to co-activate the two NP receptors, particulate guanylyl cyclase (pGC)-A and pGC-B. The rationale for it...

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Detalhes bibliográficos
Publicado no:Int J Cardiol
Main Authors: Ichiki, Tomoko, Dzhoyashvili, Nina, Burnett, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277229/
https://ncbi.nlm.nih.gov/pubmed/29941213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2018.06.002
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